HONGKONG XINRUNDE CHEMICAL CO., LTD.  

Product Name: High Purity Tacrolimus Powder as Antibiotic CAS 104987-11-3 with Best Price Model NO.: 104987-11-3 Purity: >99% State: Solid Suitable for: Adult Certification: USP, BP Customized: Customized Powder: Yes CAS Number: CAS 104987-11-3 Key Words: Tacrolimus Type: Pharmaceutical Intermediates Usage: Pharmaceutical Raw Material Appearance: White Powder Alias: Tsukubaenolide Manufacturer: Tacrolimus Manufacturer Assay: 99% Tacrolimus Package: 1-2 Kg / Aluminum Foil Bag, 25kg/ Drum, as Require Trademark: XRD Transport Package: 1-2 Kg / Aluminum Foil Bag, 25kg/ Drum, as Require Specification: 99% Tacrolimus Origin: China HS Code: 3002200000 Product Description High Purity Tacrolimus Powder as Antibiotic CAS 104987-11-3 with best priceBasic info:TacrolimusPurity: 99%CAS: 104987-11-3MF: C44H69NO12MW: 804.02Melting Point: 113-115° CBoiling Point: 871.7 ° C at 760 mmHgAppearance: White powderLead time: 1-2 days upon receipt of paymentDelivery time: Usually 4-6 working days by airStorage: Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container.Application:L Immunosuppression following transplantation It has similar immunosuppressive properties to ciclosporin, but is much more potent. Immunosuppression with tacrolimus was associated with a significantly lower rate of acute rejection compared with ciclosporin-based immunosuppression (30.7% vs 46.4%) in one study. Clinical outcome is better with tacrolimus than with ciclosporin during the first year of liver transplantation. Long term outcome has not been improved to the same extent. Tacrolimus is normally prescribed as part of a post-transplant cocktail including steroids, mycophenolate and IL-2 receptor inhibitors. Dosages are titrated to target blood levels. Typical starting doses for once daily tacrolimus are 0.15-0.20 mg/kg body weight.Interactions :Also like cyclosporin it has a wide range of interactions, including that with grapefruit which increases plasma-tacrolimus concentration. Several of the newer class of antifungals, especially of the azole class (fluconazole, posaconazole) also increase drug levels by competing for degradative enzymes.Dermatological Use:As an ointment, tacrolimus is used in the treatment of eczema, in particular atopic dermatitis. It suppresses inflammation in a similar way to steroids, and is equally as effective as a mid-potency steroid. An important advantage of tacrolimus is that, unlike steroids, it does not cause skin thinning (atrophy), or other steroid related side-effects.It is applied on the active lesions until they heal off, but may also be used continuously in low doses (twice a week), and applied to the thinner skin over the face and eyelids[citation needed]. Clinical trials of up to one year have been conducted. Recently it has also been used to treat segmental vitiligo in children, especially in areas on the face.Specifications:TestSpecificationResultDescriptionA white crystalline powderCompliesSolubilitySoluble in Methanol, Ethyl acetate and ChloroformCompliesWater≤3.0%1.3%Residue on ignition≤0.10%CompliesHeavy metals<10ppmCompliesIsomer≤5.0%0.56%Individual Impurity≤0.5%0.33%T otalimpurities≤2.0%0.43%Assay ( on dry basisincluding isomers)≥98.0%99.8%ConclusionThe product conforms to the Enterprise specification.COA:Items of analysisSpecificationResultsDescriptiona white to off-white powderwhite powderBy IR spectroscopyIR spectrum of sample should match with standard IR spectrumconformsby HPLCthe retention time of the major peak of the sample solution corresponds to that of the standard solution as obtained in the assaycoformsloss on dryingnot more than 4.0%2.2%residue on ignitionnot more than 0.2%0.04%heavy metalsnot more than 20ppmless than 20ppmspecific optical rotaion-80 ° to -90 °-89 °any individual impuritynot more than 0.5%0.08%total impuritynot more than 1.0%0.25%assay by HPLC98.0%-102.0%99.0%Packing:Advantages:HongkongXinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.2. Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.3. Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and toinsure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate4. Warm after-sale service Any of your question would be solved for the first as soon as possible.High Purity Tacrolimus Powder as Antibiotic CAS 104987-11-3 with best price